{"id":502,"date":"2022-08-12T02:33:18","date_gmt":"2022-08-12T02:33:18","guid":{"rendered":"https:\/\/blog.nootopia.com\/?p=502"},"modified":"2022-08-30T22:43:17","modified_gmt":"2022-08-30T22:43:17","slug":"how-to-increase-bdnf-naturally","status":"publish","type":"post","link":"https:\/\/nootopia.com\/blog\/how-to-increase-bdnf-naturally\/","title":{"rendered":"How to increase BDNF Naturally"},"content":{"rendered":"\n<p>The good news is that you can stimulate <a href=\"https:\/\/blog.nootopia.com\/role-of-bdnf\/\" target=\"_blank\" rel=\"noreferrer noopener\">BDNF<\/a> production and boost your brain&#8217;s BDNF levels naturally. In this article, we\u2019ll share with you how to increase your BDNF levels naturally.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">19 Ways to Increase BDNF Naturally&nbsp;<\/h2>\n\n\n\n<p>Many ways to increase BDNF are hormeses, which are stressors that make you stronger in small and healthy doses. In response to these stressors, your brain produces BDNF to grow and adapt. In addition, you can mix and match these hormeses in order to reap even more health benefits, including greater increases in BDNF levels.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1147184161-1-1024x683.jpg\" alt=\"\" class=\"wp-image-956\" srcset=\"https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1147184161-1-1024x683.jpg 1024w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1147184161-1-300x200.jpg 300w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1147184161-1-768x512.jpg 768w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1147184161-1-1536x1024.jpg 1536w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1147184161-1-2048x1365.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Exercise<\/h3>\n\n\n\n<p>Exercise increases neurogenesis and favorable brain responses that come with an increase in BDNF in both aged and young people.<span class=\"custom-citation\" data-id=\"ref-1\"><\/span><span class=\"custom-citation\" data-id=\"ref-2\"><\/span>&nbsp;<\/p>\n\n\n\n<p>Longer exercise sessions increase BDNF more, but even 10 minutes of intense exercise can somewhat increase BDNF and improve your cognitive function.<span class=\"custom-citation\" data-id=\"ref-3\"><\/span><\/p>\n\n\n\n<p>However, this is not a quick fix, as BDNF can fall to pre-exercise levels in 30 &#8211; 50 minutes. Therefore, to sustainably increase BDNF, you should exercise regularly.<span class=\"custom-citation\" data-id=\"ref-4\"><\/span> If you wish to step it up, working out in a hot room even further increases your BDNF levels than exercising alone.<span class=\"custom-citation\" data-id=\"ref-5\"><\/span>&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"540\" src=\"https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1347836420-1-1024x540.jpg\" alt=\"Shot of a man using a medicine ball during his workout in the gym\" class=\"wp-image-949\" srcset=\"https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1347836420-1-1024x540.jpg 1024w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1347836420-1-300x158.jpg 300w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1347836420-1-768x405.jpg 768w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1347836420-1-1536x810.jpg 1536w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1347836420-1-2048x1080.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Heat exposure<\/h3>\n\n\n\n<p>Hyperthermic conditioning is the process of continuous exposure to high temperatures for a short time. You can get hypothermic conditioning from any type of heat exposure, including, steam saunas, dry saunas, hot baths, and <a href=\"https:\/\/bioptimizers.com\/blog\/how-to-boost-your-immune-system\/\" target=\"_blank\" rel=\"noreferrer noopener\">infrared saunas<\/a>.<span class=\"custom-citation\" data-id=\"ref-6\"><\/span> Any of these heat exposures can increase your BDNF.<span class=\"custom-citation\" data-id=\"ref-6\"><\/span>\u00a0<\/p>\n\n\n\n<p>Infrared saunas expose the human body to as high temperatures as 60\u00b0C for at least 15 minutes, typically increasing core body temperature by around 1\u00b0C. <span class=\"custom-citation\" data-id=\"ref-6\"><\/span><\/p>\n\n\n\n<p>In addition, rat studies show that infrared lights on the brain show antidepressant and anti-anxiety effects partly by improving hippocampal neurogenesis and increasing BDNF levels.<span class=\"custom-citation\" data-id=\"ref-7\"><\/span><\/p>\n\n\n\n<p>Your BDNF levels increase either by performing exercise in a hot room, enjoying your day submerged in hot water, or relaxing in infrared saunas.<span class=\"custom-citation\" data-id=\"ref-5\"><\/span><span class=\"custom-citation\" data-id=\"ref-5\"><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Stress management<\/h3>\n\n\n\n<p>BDNF levels decrease in response to stress, so it is important to keep your stress levels in check.<span class=\"custom-citation\" data-id=\"ref-8\"><\/span> Proper nutrition and exercise aid in stress management and enhance cognitive function.<span class=\"custom-citation\" data-id=\"ref-9\"><\/span>&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Intermittent fasting<\/h3>\n\n\n\n<p>Intermittent fasting is defined as not consuming food or caloric beverages for twelve or more consecutive hours.<span class=\"custom-citation\" data-id=\"ref-10\"><\/span><span class=\"custom-citation\" data-id=\"ref-11\"><\/span>&nbsp;<\/p>\n\n\n\n<p>It reduces oxidative stress and inflammation, all of which connect to increased production of BDNF.<span class=\"custom-citation\" data-id=\"ref-12\"><\/span><span class=\"custom-citation\" data-id=\"ref-13\"><\/span> It also helps with BDNF levels by improving <a href=\"https:\/\/bioptimizers.com\/shop\/products\/blood-sugar-breakthrough\" target=\"_blank\" rel=\"noreferrer noopener\">blood sugar control<\/a>. <span class=\"custom-citation\" data-id=\"ref-13\"><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Ketosis<\/h3>\n\n\n\n<p>Ketosis delivers similar anti-aging and cognitive enhancement benefits as intermittent fasting, except with more ketones to fuel the brain.<span class=\"custom-citation\" data-id=\"ref-14\"><\/span> Naturally, you may also enter ketosis while fasting.&nbsp;<\/p>\n\n\n\n<p>When the body is in ketosis, ketone bodies aid in the production of BDNF.<span class=\"custom-citation\" data-id=\"ref-2\"><\/span><\/p>\n\n\n\n<p>A ketogenic diet decreases neuronal death in the presence of inflammation and excess glutamate. Also, ketone bodies have antioxidant and anti-inflammatory properties.<span class=\"custom-citation\" data-id=\"ref-15\"><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Deep sleep<\/h3>\n\n\n\n<p>Our body goes through four sleep stages, including rapid eye movement (REM) and non-rapid eye movement (NREM).<span class=\"custom-citation\" data-id=\"ref-16\"><\/span>&nbsp;<\/p>\n\n\n\n<p>Sleep is divided into five stages:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Wake<\/li><li>N1 (Stage 1)<\/li><li>N2 (Stage 2)<\/li><li>N3 (Stage 3) or deep sleep<\/li><li>R or REM Sleep. <span class=\"custom-citation\" data-id=\"ref-16\"><\/span><\/li><\/ul>\n\n\n\n<p>Stage 3 (N3) is the deepest stage of sleep. This is the hardest stage to wake up from.<span class=\"custom-citation\" data-id=\"ref-16\"><\/span> REM sleep enhances learning and memory.<span class=\"custom-citation\" data-id=\"ref-17\"><\/span> Lack of sleep in stages N3 and R lower BDNF levels.<span class=\"custom-citation\" data-id=\"ref-18\"><\/span><\/p>\n\n\n\n<p>Sleep problems affect physical and mental health, and increase stress vulnerability.<span class=\"custom-citation\" data-id=\"ref-19\"><\/span><\/p>\n\n\n\n<p>Reduction in BDNF levels is connected to poor sleep quality. Because sleep deprivation is stressful to your body, it lowers BDNF.<span class=\"custom-citation\" data-id=\"ref-20\"><\/span>&nbsp;<\/p>\n\n\n\n<p>Sleep deprivation (along with chronic stress) may increase anxiety, insomnia, and depression.<span class=\"custom-citation\" data-id=\"ref-21\"><\/span> Thus, getting enough sleep for your brain and body is crucial for all aspects of health, including BDNF levels.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1300333569-1-1024x683.jpg\" alt=\"Sleeping charming woman dreaming in her bed\" class=\"wp-image-950\" srcset=\"https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1300333569-1-1024x683.jpg 1024w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1300333569-1-300x200.jpg 300w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1300333569-1-768x512.jpg 768w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1300333569-1-1536x1024.jpg 1536w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1300333569-1-2048x1366.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Sunlight exposure<\/h3>\n\n\n\n<p>Our BDNF levels tend to shift with the seasons.<span class=\"custom-citation\" data-id=\"ref-22\"><\/span> BDNF concentrations tend to increase in the spring and summer, while decreasing in the fall and winter.<span class=\"custom-citation\" data-id=\"ref-22\"><\/span> In addition to boosting BDNF, the sun increases vitamin D production and improves mood.<span class=\"custom-citation\" data-id=\"ref-22\"><\/span>&nbsp;<\/p>\n\n\n\n<p>Only 20 minutes of exposure to natural light is enough to increase your BDNF levels. Therefore, it is important to get some sun during the day and avoid being in enclosed and dark spaces all day.<span class=\"custom-citation\" data-id=\"ref-1\"><\/span>&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Nootropic supplements that boost BDNF<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Curcumin\/turmeric&nbsp;<\/h3>\n\n\n\n<p>Turmeric is a spice that originated in India and has been used for thousands of years. It has many medicinal properties due to curcumins and turmerones, which have antioxidants and inflammation-balancing properties.<span class=\"custom-citation\" data-id=\"ref-23\"><\/span>&nbsp;<\/p>\n\n\n\n<p>Curcumin increases cell viability and balances inflammatory responses in the brain.<span class=\"custom-citation\" data-id=\"ref-24\"><\/span> Turmeric curcumin supplements increase BDNF levels and may help with mood due to these properties.<span class=\"custom-citation\" data-id=\"ref-25\"><\/span>&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Fish oil\/omega-3 fatty acids<\/h3>\n\n\n\n<p>Omega-3 fatty acids are important components of neural cell membranes and myelin sheath, which are critical for healthy neuronal signals.&nbsp; Fish intake or omega-3 supplementation, reduces inflammation, oxidation, and cell death. This benefits proper neuronal functioning and development.<span class=\"custom-citation\" data-id=\"ref-26\"><\/span><span class=\"custom-citation\" data-id=\"ref-27\"><\/span><\/p>\n\n\n\n<p>Omega-3 (found in fish oil) enhances cognitive functioning.<span class=\"custom-citation\" data-id=\"ref-28\"><\/span> By decreasing oxidative stress, omega-3 maintains neuronal function and plasticity. This action increases BDNF levels.<span class=\"custom-citation\" data-id=\"ref-29\"><\/span><span class=\"custom-citation\" data-id=\"ref-30\"><\/span>&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Cacao<\/h3>\n\n\n\n<p>Cocoa contains flavonoids that can enter the brain to protect neurons and enhance cognitive function.<span class=\"custom-citation\" data-id=\"ref-31\"><\/span><span class=\"custom-citation\" data-id=\"ref-32\"><\/span> The antioxidant and neuroprotective properties of cocoa aid in BDNF production.<span class=\"custom-citation\" data-id=\"ref-32\"><\/span>&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1296269276-1-1024x683.jpg\" alt=\" Cocoa fruit farming production and agriculture concept.\" class=\"wp-image-951\" srcset=\"https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1296269276-1-1024x683.jpg 1024w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1296269276-1-300x200.jpg 300w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1296269276-1-768x512.jpg 768w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1296269276-1-1536x1024.jpg 1536w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1296269276-1-2048x1365.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Coffee fruit extract (including caffeine and teacrine)<\/h3>\n\n\n\n<p>Generally speaking, caffeine enhances cognitive function\u2014learning, memory, attention, mood, and BDNF levels.<span class=\"custom-citation\" data-id=\"ref-33\"><\/span> Coffee fruit extract comes from coffee berries and contains less caffeine than the average cup of coffee.<span class=\"custom-citation\" data-id=\"ref-34\"><\/span><span class=\"custom-citation\" data-id=\"ref-35\"><\/span> Nevertheless, coffee fruit greatly increases BDNF levels.<span class=\"custom-citation\" data-id=\"ref-34\"><\/span>&nbsp;<\/p>\n\n\n\n<p>Theacrine is present in coffee and tea, along with fruits and herbs. It enhances cognitive functions.<span class=\"custom-citation\" data-id=\"ref-36\"><\/span><span class=\"custom-citation\" data-id=\"ref-37\"><\/span> It also potently increases BDNF.<span class=\"custom-citation\" data-id=\"ref-38\"><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Green tea<\/h3>\n\n\n\n<p>Green tea contains many antioxidants with neuroprotective effects and a source of caffeine. We owe these properties of green tea thanks to the presence of polyphenol within it, particularly epigallocatechin-3-gallate (EGCG).<span class=\"custom-citation\" data-id=\"ref-39\"><\/span><\/p>\n\n\n\n<p>Green tea, especially EGCG, effectively increases BDNF levels.<span class=\"custom-citation\" data-id=\"ref-39\"><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Fruit polyphenols (resveratrol and polyphenols in blueberries)<\/h3>\n\n\n\n<p>Resveratrol is an important polyphenol with anti-aging and anti-inflammatory properties. Resveratrol can significantly boost BDNF levels.<span class=\"custom-citation\" data-id=\"ref-40\"><\/span>&nbsp;<\/p>\n\n\n\n<p>Blueberries and red wine are great sources of resveratrol. However, you may need to eat 10,000 blueberries to get enough resveratrol, so supplementation is the only way to get sufficient doses to improve your BDNF levels.<span class=\"custom-citation\" data-id=\"ref-41\"><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Magnesium<\/h3>\n\n\n\n<p><a href=\"https:\/\/bioptimizers.com\/shop\/products\/magnesium-breakthrough\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Magnesium<\/a> is important for over 300 biochemical pathways in the body, including in the cardiovascular, neuromuscular, and nervous systems.<span class=\"custom-citation\" data-id=\"ref-42\"><\/span> In the nervous system, it is especially important for nerve transmission and neuromuscular conduction.<span class=\"custom-citation\" data-id=\"ref-43\"><\/span><\/p>\n\n\n\n<p>Increasing brain magnesium improves memory and learning ability.<span class=\"custom-citation\" data-id=\"ref-42\"><\/span> Not only is <a href=\"https:\/\/bioptimizers.com\/blog\/what-is-a-magnesium-supplement-good-for\/\">magnesium<\/a> mood-boosting but it also increases BDNF levels.<span class=\"custom-citation\" data-id=\"ref-44\"><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">L-theanine<\/h3>\n\n\n\n<p>L-theanine is an amino acid with a calming effect found in green tea <span class=\"custom-citation\" data-id=\"ref-45\"><\/span> It has neuroprotective activity (antioxidant activity).<span class=\"custom-citation\" data-id=\"ref-46\"><\/span><span class=\"custom-citation\" data-id=\"ref-47\"><\/span> L-theanine is a cognitive enhancer that boosts alertness, mood, and attention span partly by increasing BDNF levels.<span class=\"custom-citation\" data-id=\"ref-46\"><\/span><span class=\"custom-citation\" data-id=\"ref-47\"><\/span><span class=\"custom-citation\" data-id=\"ref-48\"><\/span>&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Ginseng<\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"684\" src=\"https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1027128646-1-1024x684.jpg\" alt=\"Gingsen root and tea\" class=\"wp-image-952\" srcset=\"https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1027128646-1-1024x684.jpg 1024w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1027128646-1-300x200.jpg 300w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1027128646-1-768x513.jpg 768w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1027128646-1-1536x1026.jpg 1536w, https:\/\/nootopia.com\/blog\/wp-content\/uploads\/2022\/08\/GettyImages-1027128646-1-2048x1368.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>Ginseng is one of the most adaptogenic herbs. Panax ginseng is the most common ginseng example.<span class=\"custom-citation\" data-id=\"ref-49\"><\/span>&nbsp;<\/p>\n\n\n\n<p>Panax ginseng contains ginsenosides\u2014abundant with anti-inflammatory and antioxidant properties.<span class=\"custom-citation\" data-id=\"ref-49\"><\/span> These properties contribute to neuroprotection and preservation.<span class=\"custom-citation\" data-id=\"ref-50\"><\/span><\/p>\n\n\n\n<p>Ginsenosides improve energy levels and promote calmness amidst stress.<span class=\"custom-citation\" data-id=\"ref-50\"><\/span> It also plays a role in cell viability\u2014promotes cell survival.<span class=\"custom-citation\" data-id=\"ref-51\"><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Noopept<\/h3>\n\n\n\n<p>Noopept is a small peptide-like molecule similar to piracetam. It has high cognition-enhancing and neuroprotective effects, meaning that noopept increases the survival of neurons.<span class=\"custom-citation\" data-id=\"ref-52\"><\/span><\/p>\n\n\n\n<p>Noopept directly stimulates BDNF production in neurons.<span class=\"custom-citation\" data-id=\"ref-53\"><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Synbiotics and butyrate<\/h3>\n\n\n\n<p><a href=\"https:\/\/bioptimizers.com\/shop\/products\/cognibiotics\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Synbiotics<\/a> are probiotics and prebiotics mixtures that work together to provide health benefits to the consumer. They can improve your gut flora composition better than probiotics alone.<span class=\"custom-citation\" data-id=\"ref-54\"><\/span>&nbsp;<\/p>\n\n\n\n<p>Inflammation in the brain and low BDNF levels are linked to age-related cognitive impairment.<span class=\"custom-citation\" data-id=\"ref-55\"><\/span> Synbiotic supplementation counteracts these processes by increasing BDNF, promoting a balanced immune response in the brain, and increasing neurogenesis.<span class=\"custom-citation\" data-id=\"ref-55\"><\/span><\/p>\n\n\n\n<p>Butyrate is a byproduct of microbial fermentation of dietary fibers.<span class=\"custom-citation\" data-id=\"ref-56\"><\/span> Not only does it support the gut barrier but also increases neurogenesis and BDNF levels.<span class=\"custom-citation\" data-id=\"ref-54\"><\/span> Therefore, it may help with cognitive impairment.<span class=\"custom-citation\" data-id=\"ref-57\"><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Lithium<\/h3>\n\n\n\n<p>Lithium is also particularly well known for its ability to increase levels of BDNF.<span class=\"custom-citation\" data-id=\"ref-58\"><\/span> It protects neurons and reduces cell death.<span class=\"custom-citation\" data-id=\"ref-59\"><\/span><\/p>\n\n\n\n<p>Lithium stimulates hippocampal neurogenesis.<span class=\"custom-citation\" data-id=\"ref-59\"><\/span> It enhances cognitive functions and overall mental performance.<span class=\"custom-citation\" data-id=\"ref-59\"><\/span>&nbsp;Lithium has a remarkable influence on cells. Apart from protecting cells, it induces cellular repair and regeneration.<span class=\"custom-citation\" data-id=\"ref-60\"><\/span><\/p>\n\n\n\n<p>To learn more about BDNF, check out parts 1 and 2 of our 3-part series:<\/p>\n\n\n\n<p>Part 1: <a href=\"https:\/\/blog.nootopia.com\/role-of-bdnf\/\" target=\"_blank\" rel=\"noreferrer noopener\">What is BDNF and its roles in the brain<\/a><\/p>\n\n\n\n<p>Part 2: How to know if you have low BDNF and what could be the reasons<\/p>\n\n\n\n<p>References:<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li><div id=\"ref-1\" class=\"custom-reference\">Kwon SJ, Park J, Park SY, et al. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4145925\/\" target=\"_blank\" rel=\"noreferrer noopener\">Low-intensity treadmill exercise and\/or bright light promote neurogenesis in adult rat brain<\/a>. <em>Neural Regen Res<\/em>. 2013;8(10):922-929. doi:10.3969\/j.issn.1673-5374.2013.10.007 <\/div><\/li><li><div id=\"ref-2\" class=\"custom-reference\">Sleiman SF, Henry J, Al-Haddad R, et al. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4915811\/\" target=\"_blank\" rel=\"noreferrer noopener\">Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body \u03b2-hydroxybutyrate<\/a>. <em>Elife<\/em>. 2016;5. doi:10.7554\/eLife.15092 <\/div><\/li><li><div id=\"ref-3\" class=\"custom-reference\">Schmolesky MT, Webb DL, Hansen RA. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3772595\/\" target=\"_blank\" rel=\"noreferrer noopener\">The effects of aerobic exercise intensity and duration on levels of brain-derived neurotrophic factor in healthy men<\/a>. <em>J Sports Sci Med<\/em>. 2013;12(3):502-511. <\/div><\/li><li><div id=\"ref-4\" class=\"custom-reference\">De la Rosa A, Solana E, Corpas R, et al. <a href=\"https:\/\/www.nature.com\/articles\/s41598-019-40040-8\" target=\"_blank\" rel=\"noreferrer noopener\">Long-term exercise training improves memory in middle-aged men and modulates peripheral levels of BDNF and Cathepsin B<\/a>. <em>Sci Rep<\/em>. 2019;9(1):3337. doi:10.1038\/s41598-019-40040-8 <\/div><\/li><li><div id=\"ref-5\" class=\"custom-reference\">Kojima D, Nakamura T, Banno M, et al. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29157042\/\" target=\"_blank\" rel=\"noreferrer noopener\">Head-out immersion in hot water increases serum BDNF in healthy males<\/a>. <em>Int J Hyperthermia<\/em>. 2018;34(6):834-839. doi:10.1080\/02656736.2017.1394502 <\/div><\/li><li><div id=\"ref-6\" class=\"custom-reference\">Glazachev OS, Zapara MA, Dudnik EN, Samartseva VG, Susta D. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32365000\/\" target=\"_blank\" rel=\"noreferrer noopener\">Repeated hyperthermia exposure increases circulating Brain Derived Neurotrophic Factor levels which is associated with improved quality of life, and reduced anxiety: A randomized controlled trial<\/a>. <em>J Therm Biol<\/em>. 2020;89(102482):102482. doi:10.1016\/j.jtherbio.2019.102482 <\/div><\/li><li><div id=\"ref-7\" class=\"custom-reference\">Tanaka Y, Akiyoshi J, Kawahara Y, et al. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21511206\/\" target=\"_blank\" rel=\"noreferrer noopener\">Infrared radiation has potential antidepressant and anxiolytic effects in animal model of depression and anxiety.<\/a> <em>Brain Stimul<\/em>. 2011;4(2):71-76. doi:10.1016\/j.brs.2010.04.001 <\/div><\/li><li><div id=\"ref-8\" class=\"custom-reference\">Murakami S, Imbe H, Morikawa Y, Kubo C, Senba E. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16024125\/\" target=\"_blank\" rel=\"noreferrer noopener\">Chronic stress, as well as acute stress, reduces BDNF mRNA expression in the rat hippocampus but less robustly<\/a>. <em>Neurosci Res<\/em>. 2005;53(2):129-139. doi:10.1016\/j.neures.2005.06.008 <\/div><\/li><li><div id=\"ref-9\" class=\"custom-reference\">Worthen M, Cash E. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30020672\/\" target=\"_blank\" rel=\"noreferrer noopener\">Stress Management<\/a>. 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